Related Experiment Video
Updated: Mar 16, 2026
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Lymphangioleiomyomatosis
Simon R Johnson1, Angelo M Taveira-DaSilva2, Joel Moss3
1Division of Respiratory Medicine, National Centre for Lymphangioleiomyomatosis, University Hospitals NHS Trust, University of Nottingham, Nottingham, NG7 2UH, UK.
Abstract:
Lymphangioleiomyomatosis is a rare multisystem disease predominantly affecting women that can occur sporadically or in association with tuberous sclerosis. Lung cysts progressively replace the lung parenchyma, which leads to dyspnea, recurrent pneumothorax, and in some cases respiratory failure. Patients may also have lymphatic disease in the thorax, abdomen, and pelvis, and renal angiomyolipomas. Treatment includes supportive care, bronchodilators, and for those with progressive disease, mammalian target of rapamycin (mTOR) inhibitors.
