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Updated: Mar 16, 2026
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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
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Nonmalignant Adult Thoracic Lymphatic Disorders
Maxim Itkin1, Francis X McCormack2
1Interventional Radiology, Hospital of the University of Pennsylvania, Penn Medicine, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Clinics in Chest Medicine
|August 13, 2016
Summary
Thoracic lymphatic disorders, uncommon conditions affecting the chest, are being redefined by advanced imaging. New techniques improve diagnosis, guiding novel treatments like embolization and drug therapy.
Area of Science:
- Medical imaging
- Thoracic medicine
- Lymphatic system research
Background:
- Thoracic lymphatic disorders are rare and diverse conditions.
- They present with thoracic masses, lung infiltrates, and chylous issues.
- Accurate diagnosis is crucial for effective management.
Purpose of the Study:
- To highlight the significance of accurate diagnosis in thoracic lymphatic disorders.
- To introduce novel diagnostic and therapeutic strategies.
- To emphasize the role of advanced imaging in understanding lymphatic flow.
Main Methods:
- Review of current understanding of thoracic lymphatic disorders.
- Discussion of emerging imaging techniques, specifically dynamic contrast-enhanced magnetic resonance lymphangiogram.
- Exploration of new management approaches.
Main Results:
- Advanced imaging techniques are enhancing the characterization of lymphatic flow.
- These advancements are leading to a reclassification of disease.
- Improved diagnostic capabilities are informing new therapeutic interventions.
Conclusions:
- Accurate diagnosis of thoracic lymphatic disorders is critical for modern management.
- Dynamic contrast-enhanced magnetic resonance lymphangiogram is a key imaging innovation.
- New therapeutic options, including embolization and antilymphangiogenic drugs, are emerging.
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