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Eosinophilic Lung Diseases

Vincent Cottin¹

¹Hospices Civils de Lyon, Louis Pradel Hospital, National Reference Center for Rare Pulmonary Diseases, Department of Respiratory Diseases, F-69677 Lyon, France; Univ Lyon, Université Lyon I, INRA, UMR754, 8 avenue Rockefeller, F-69008 Lyon, France.

Clinics in Chest Medicine

|August 13, 2016

Abstract:

Eosinophilic lung diseases especially comprise eosinophilic pneumonia or as the more transient Löffler syndrome, which is most often due to parasitic infections. The diagnosis of eosinophilic pneumonia is based on characteristic clinical-imaging features and the demonstration of alveolar eosinophilia, defined as at least 25% eosinophils at BAL. Peripheral blood eosinophilia is common but may be absent at presentation in idiopathic acute eosinophilic pneumonia, which may be misdiagnosed as severe infectious pneumonia. All possible causes of eosinophilia, including drug, toxin, fungus related etiologies, must be thoroughly investigated. Extrathoracic manifestations should raise the suspicion of eosinophilic granulomatosis with polyangiitis.

Keywords:

Aspergillus Eosinophil Eosinophilic granulomatosis with polyangiitis Eosinophilic pneumonia Interstitial lung disease

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