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Development of new malaria diagnostics: matching performance and need.

David Bell1, Alessandra E Fleurent2, Michael C Hegg3

  • 1Global Good Fund/Intellectual Ventures Laboratory, 3150 139th Ave SE, Bellevue, WA, 98005, USA. dbell@intven.com.

Malaria Journal
|August 13, 2016
PubMed
Summary

Accurate malaria diagnosis remains a challenge, with few new technologies reaching the field. Understanding market needs and engaging stakeholders are crucial for developing and implementing effective malaria diagnostic tools.

Keywords:
MalariaMalaria diagnostics marketRapid diagnostic testingTarget product profiles

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Area of Science:

  • Global Health
  • Medical Diagnostics
  • Parasitology

Background:

  • Significant gaps persist in accessing accurate malaria diagnosis, leading to resource waste and poor disease management, particularly in low-resourced settings.
  • Despite substantial investment, few novel malaria diagnostic technologies have been introduced in the last 30 years, indicating potential misdirection in development efforts or barriers to adoption.
  • The malaria diagnostic market is complex, influenced by donor dependency, weak health systems, and evolving program priorities, hindering the successful introduction of new tools.

Discussion:

  • Development efforts for malaria diagnostics need to align with specific market requirements to improve product development funding outcomes.
  • Six distinct market segments for malaria diagnostics are identified, ranging from case management in resource-limited areas to surveillance and clinical research.
  • The variable market sizes and evolving nature of malaria epidemiology necessitate a clear understanding of program gaps and market sustainability.

Key Insights:

  • Successful malaria diagnostic development requires a strategic approach, focusing on clearly defined market needs and segments.
  • Addressing fundamental blocks to technology introduction is essential for improving access to accurate malaria diagnosis.
  • Collaboration among diverse stakeholders is vital for the successful introduction and scaling of new diagnostic technologies.

Outlook:

  • Future success in malaria diagnostics hinges on innovative business models and potential donor involvement to overcome economic challenges.
  • Targeting assay development to specific, well-defined market requirements will enhance the impact of R&D funding.
  • A concerted effort involving stakeholders is necessary to ensure the widespread adoption and scaling of new malaria diagnostic solutions.