Influenza B/Streptococcal co-infection complicated by organizing pneumonia
Wang C Kwok1, Sonia H Y Lam2, Maria P Wong3
1Department of Medicine Queen Mary Hospital, University of Hong Kong Hong Kong SAR China.
Abstract:
Organizing pneumonia is a rare complication of influenza infection that has substantial morbidity. We report the first case of organizing pneumonia associated with influenza B and Streptococcus pneumoniae coinfection that had significant improvement with corticosteroid treatment. The clinical and radiological features of organizing pneumonia associated with this coinfection are similar to those after influenza A infection. Timely use of systemic glucocorticosteroids would be of benefit in promoting resolution for influenza-associated organizing pneumonia.
Insights
Organizing pneumonia is a rare influenza complication. This case highlights successful treatment with corticosteroids for influenza B and Streptococcus pneumoniae coinfection, suggesting their benefit in similar influenza-associated cases.
Area of Science:
- Pulmonology
- Infectious Diseases
- Critical Care Medicine
Background:
- Organizing pneumonia (OP) is a rare but serious complication of influenza infections, leading to significant patient morbidity.
- While OP is known to occur after influenza A, its association with influenza B and bacterial coinfection is less documented.
Observation:
- This report details the first case of organizing pneumonia following coinfection with influenza B and Streptococcus pneumoniae.
- The patient presented with clinical and radiological features mirroring those seen in influenza A-associated OP.
Findings:
- The coinfection of influenza B and Streptococcus pneumoniae led to organizing pneumonia.
- Treatment with systemic corticosteroids resulted in significant clinical and radiological improvement.
Implications:
- The findings suggest that clinical and radiological manifestations of OP due to influenza B/Streptococcus pneumoniae coinfection are similar to those seen with influenza A.
- Early administration of systemic glucocorticosteroids may be beneficial for resolving influenza-associated organizing pneumonia, regardless of the specific influenza strain or coinfecting bacteria.
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