Related Experiment Video
Updated: Mar 16, 2026

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
Published on: October 12, 2017
Secondary or Transient Pseudohypoaldosteronism Associated With Urinary Tract Anomaly and Urinary Infection: A Case
Vinod Krishnappa1, Jonathan H Ross2, David N Kenagy3
1Akron Nephrology Associates/Akron General Cleveland Clinic, Akron, Ohio, USA.
Abstract:
Hyponatremia with hyperkalemia in infancy is a rare presentation, but may be due to aldosterone deficiency or end organ resistance to its action. There are few cases associating this condition with urinary tract infections or anatomic abnormalities that predispose to infection. Clinicians should have a high index of suspicion in diagnosing secondary pseudohypoaldosteronism (PHA) due to its often atypical presentation. We describe ten month-old infant who presented with this condition and was found to have urinary tract infection complicating unilateral urinary tract anomaly, which may have strong association with renal tubular resistance to aldosterone.
Related Concept Videos
Urinary Tract Infection II: Pathophysiology
Acute Pyelonephritis I: Introduction
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection I: Introduction
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...

