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Updated: Mar 16, 2026
Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles
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Fe3O4@SiO2 core-shell nanoparticles for biomedical purposes: adverse effects on blood cells
C Achilli1, S Grandi, G F Guidetti
1University of Pavia, Department of Biology and Biotechnology, Laboratories of Biochemistry, via Bassi 21, Pavia, Italy. minetti@unipv.it.
Abstract:
Magnetite nanoparticles coated with silica, obtained by a sol-gel process in the reverse micelle microemulsion, were characterized and homogeneously suspended in water in order to assay their biocompatibility toward blood cells, in view of a potential medical use of this material. Their hemolytic, pro-thrombotic and pro-inflammatory properties were observed.
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