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The incidence of deep venous thrombosis after total hip replacement using Dextran 70 prophylaxis-A venographic study

F McManus1

  • 1Cappagh Orthopaedic Hospital and Joint Replacement Centre, Finglas, Dublin.

Irish Journal of Medical Science
|August 13, 2016
PubMed

Insights

This study investigated deep vein thrombosis (DVT) in hip replacement patients. Dextran 70 prophylaxis did not eliminate DVT, with a 6.6% incidence found on post-operative day nine.

Area of Science:

  • Orthopedic Surgery
  • Vascular Medicine
  • Thrombosis Research

Background:

  • Deep vein thrombosis (DVT) is a significant risk following hip arthroplasty.
  • Effective prophylaxis strategies are crucial to mitigate post-operative complications.

Purpose of the Study:

  • To determine the incidence of deep vein thrombosis (DVT) in patients undergoing Charnley low friction arthroplasty.
  • To evaluate the efficacy of Dextran 70 prophylaxis in preventing DVT.

Main Methods:

  • Bilateral venography was performed on the ninth post-operative day.
  • Sixty consecutive patients receiving Charnley low friction arthroplasty were included.
  • All patients received Dextran 70 as deep vein thrombosis prophylaxis.

Main Results:

  • An overall incidence of 6.6% for deep vein thrombosis was identified.
  • The prophylaxis regimen did not completely prevent DVT formation.

Conclusions:

  • Dextran 70 prophylaxis demonstrated a limited efficacy in preventing deep vein thrombosis after hip arthroplasty.
  • Further investigation into alternative or adjunctive prophylactic measures is warranted.

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