Related Experiment Video
Updated: Mar 16, 2026

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
Published on: March 22, 2024
Venous catheter associated candida albicans septicaemia
M T Clancy1, J Gad-Al-Rab1, C T Keane1
1Department of Medical Microbiology and Histopathology, Federated Dublin Voluntary Hospitals and Trinity College, Dublin.
Abstract:
Opportunistic fungal infection is recognised as a complication of intravenous therapy (Zinneret al., 1969), prolonged antibiotic usage, immuno-suppressives, steroids, radiotherapy and in patients whose host defences are impaired (Klainer and Beisel, 1969). We describe here a patient with Hodgkin's disease who developed disseminated candidiasis associated with an indwelling venous catheter.
Insights
Opportunistic fungal infections can occur in immunocompromised patients. This case study highlights disseminated candidiasis in a Hodgkin
Area of Science:
- Medical Mycology
- Infectious Diseases
- Hematology
Background:
- Opportunistic fungal infections are known complications in patients with compromised immune systems.
- Risk factors include intravenous therapy, prolonged antibiotic use, immunosuppressive medications, steroids, and radiotherapy.
- Impaired host defenses significantly increase susceptibility to fungal pathogens.
Purpose of the Study:
- To report a case of disseminated candidiasis in a patient with Hodgkin's disease.
- To investigate the association between an indwelling venous catheter and fungal infection development.
Main Methods:
- Case report detailing clinical presentation and management.
- Review of patient's medical history, including Hodgkin's disease and prior treatments.
- Assessment of potential contributing factors, such as indwelling venous catheter.
Main Results:
- A patient diagnosed with Hodgkin's disease developed disseminated candidiasis.
- The fungal infection was strongly associated with the presence of an indwelling venous catheter.
- This highlights a specific clinical scenario of opportunistic infection in an immunocompromised patient.
Conclusions:
- Indwelling venous catheters can serve as a potential source for opportunistic fungal infections, particularly candidiasis.
- Patients with hematological malignancies like Hodgkin's disease are at increased risk.
- Vigilance for fungal infections is crucial in immunocompromised patients with invasive devices.
More Related Videos
08:31Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging
Published on: January 27, 2015
07:42An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020