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A Versatile Axle for the Construction of Disassemblage Rotaxanes
Lucas A Powers1, David B Smithrud2
1Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. powersla@mail.uc.edu.
Abstract:
Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and ¹H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors.
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