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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
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[Not Available].

J Kußmann1, M Koller2, T Heinke3

  • 11. Chirurgische Abteilung (Leiter: Priv.-Doz Dr. J. Kußmann) des Allgemeinen Krankenhauses Wandsbek, Hamburg, , , , , , XX.

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Summary
This summary is machine-generated.

Routine preoperative coagulation tests like PT and aPTT are not reliable predictors of postoperative bleeding. Identifying patients at risk based on medical history is more sensitive for predicting bleeding complications.

Keywords:
Key words: Preoperative coagulation studiesPostoperative bleeding.

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Area of Science:

  • Anesthesiology
  • Hematology
  • Surgical Sciences

Context:

  • Preoperative coagulation screening, including platelet count, prothrombin time (PT), and activated partial thromboplastin time (aPTT), is standard practice.
  • The utility of these routine tests in predicting postoperative bleeding remains a subject of investigation.

Purpose:

  • To retrospectively evaluate the effectiveness of common preoperative coagulation screening tests in predicting postsurgical bleeding.
  • To compare the predictive value of abnormal coagulation studies versus identifying patients with risk factors for bleeding.

Summary:

  • A retrospective study of 1447 patients undergoing abdominal and thoracic surgery found that only 3.2% experienced postoperative bleeding.
  • Abnormal coagulation studies (12.2% of patients) had a low sensitivity (23.9%) for predicting bleeding.
  • Identifying patients with risk factors for coagulopathies demonstrated higher sensitivity (56.5%) in predicting bleeding.

Impact:

  • Findings suggest that routine preoperative screening of PT and aPTT may not be beneficial for all patients.
  • Preoperative coagulation testing should be reserved for patients with known or suspected inherited or acquired coagulopathies.
  • This research may lead to more targeted and cost-effective preoperative patient assessment strategies.