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Cost Associated With Pediatric Delirium in the ICU
Chani Traube1, Elizabeth A Mauer, Linda M Gerber
11Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY.2Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY.3Weill Cornell Medical College, New York, NY.4Department of Molecular Biology, Princeton University, Princeton, NJ.5Department of Pediatrics, Weill Cornell Medical College, New York, NY.6Department of Child Psychiatry, Weill Cornell Medical College, New York, NY.
Insights
Pediatric delirium significantly increases pediatric intensive care unit (PICU) costs, with longer delirium duration leading to exponentially higher expenses. Early recognition and intervention are crucial for better patient outcomes and potential healthcare savings.
Area of Science:
- Critical care medicine
- Pediatric critical care
- Neuroscience
Background:
- Delirium is a common complication in critically ill children.
- The economic impact of pediatric delirium remains incompletely understood.
- Understanding the cost implications is vital for resource allocation and quality improvement initiatives.
Purpose of the Study:
- To quantify the association between pediatric delirium and healthcare costs within the intensive care unit.
- To determine the incremental costs associated with the duration of delirium in critically ill children.
Main Methods:
- Prospective observational study conducted in a tertiary-care pediatric intensive care unit (PICU).
- Included 464 consecutive PICU admissions over a defined period.
- Daily delirium assessments were performed, and hospital costs were analyzed using cost-to-charge ratios.
Main Results:
- Children with delirium incurred significantly higher median total PICU costs compared to those without delirium ($18,832 vs $4,803).
- Costs escalated with the number of days spent in delirium, with over 3 days associated with substantially increased expenses.
- Even after adjusting for length of stay and other factors, delirium independently predicted an 85% increase in PICU costs.
Conclusions:
- Pediatric delirium represents a significant driver of increased costs in the PICU.
- Further research into the prevention and treatment of pediatric delirium is essential.
- Effective interventions could lead to improved patient outcomes and substantial healthcare cost reductions.
Objective:
To determine the costs associated with delirium in critically ill children.
Design:
Prospective observational study.
Setting:
An urban, academic, tertiary-care PICU in New York city.
Patients:
Four-hundred and sixty-four consecutive PICU admissions between September 2, 2014, and December 12, 2014.
Interventions:
None.
Measurements And Main Results:
All children were assessed for delirium daily throughout their PICU stay. Hospital costs were analyzed using cost-to-charge ratios, in 2014 dollars. Median total PICU costs were higher in patients with delirium than in patients who were never delirious ($18,832 vs $4,803; p < 0.0001). Costs increased incrementally with number of days spent delirious (median cost of $9,173 for 1 d with delirium, $19,682 for 2-3 d with delirium, and $75,833 for > 3 d with delirium; p < 0.0001); this remained highly significant even after adjusting for PICU length of stay (p < 0.0001). After controlling for age, gender, severity of illness, and PICU length of stay, delirium was associated with an 85% increase in PICU costs (p < 0.0001).
Conclusions:
Pediatric delirium is associated with a major increase in PICU costs. Further research directed at prevention and treatment of pediatric delirium is essential to improve outcomes in this population and could lead to substantial healthcare savings.
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