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Dexamethasone implant in diabetic macular edema in real-life situations

P C Gupta1, J Ram1

  • 1Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Eye (London, England)
|August 13, 2016
PubMed
Abstract

No abstract available in PubMed .

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Ophthalmic Drug Delivery Systems01:23

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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