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Updated: Aug 6, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Radiation-induced sarcoma of the thyroid
K L Griem1, P K Robb, D D Caldarelli
1Department of Therapeutic Radiology, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
Abstract:
A 23-year-old white man presented with a thyroid mass 12 years after receiving high-dose radiotherapy for a T2 and N1 lymphoepithelioma of the nasopharynx. Following subtotal thyroidectomy, a histopathologic examination revealed liposarcoma of the thyroid gland. The relationship between sarcomas and irradiation is described and Cahan and colleagues' criteria for radiation-induced sarcomas are reviewed. To our knowledge, we are presenting the first such case of a radiation-induced sarcoma of the thyroid gland.
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