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Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
Published on: August 23, 2022
Pediatric cholangiopathies: diseases of the gallbladder and biliary tract
Mark E Sharafinski1, Arthur B Meyers2, Gregory Vorona3
1Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave., Box 09, Chicago, IL, 60611, USA. mark.sharafinski@gmail.com.
Insights
Pediatric gallbladder and bile duct diseases range from congenital to neoplastic conditions. This review focuses on non-invasive imaging, highlighting ultrasound as the primary tool for diagnosing biliary pathology in children.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Imaging
- Hepatobiliary Diseases
Background:
- Pediatric gallbladder and bile duct diseases present a wide range of conditions, including congenital, developmental, and neoplastic processes.
- Understanding normal pediatric biliary anatomy is crucial for diagnosing pathology.
Purpose of the Study:
- To summarize common pediatric gallbladder and bile duct pathologic entities.
- To focus on non-invasive imaging techniques and their findings in pediatric biliary disease.
Main Methods:
- Review of normal pediatric biliary anatomy.
- Summary of common pathologic entities.
- Emphasis on non-invasive imaging modalities: ultrasound, MRI, and MRCP.
Main Results:
- Ultrasound is the initial imaging modality of choice for suspected pediatric biliary pathology due to accessibility, cost-effectiveness, and lack of radiation.
- MRI and MRCP are valuable for further evaluation when diagnostic uncertainty exists and for surgical planning.
Conclusions:
- Non-invasive imaging, particularly ultrasound, plays a pivotal role in diagnosing pediatric biliary diseases.
- Advanced imaging like MRI/MRCP aids in complex cases and surgical preparation.
Abstract:
Pediatric gallbladder and bile duct disease encompasses a broad spectrum of processes, from congenital to developmental to neoplastic. We describe normal pediatric biliary anatomy and summarize the most common pathologic entities, with a focus on non-invasive imaging techniques and findings. Ultrasound is the first-line imaging modality in children with suspected biliary pathology based on its widespread availability, cost effectiveness, and lack of ionizing radiation. MRI and MRCP are often used for further evaluation in cases of diagnostic uncertainty and for surgical planning.
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