Monitoring of pH and PCO2 in children using the Paratrend 7 in a peripheral vein
J D Tobias1,2,3,4, D J Meyer2,4, M A Helikson1,5,4
1Department of Child Health, The University of Missouri, Columbia, Missouri.
Insights
The Paratrend 7 monitor accurately measures pH and PCO2 in children with respiratory failure when inserted into a peripheral vein, offering clinically acceptable correlations with arterial blood gas values.
Area of Science:
- Pediatric critical care medicine
- Respiratory physiology
- Medical device technology
Background:
- Continuous monitoring of blood gases is crucial for managing pediatric respiratory failure.
- Traditional arterial blood gas sampling is invasive and can be painful for children.
- The Paratrend 7 system offers a potential less invasive method for continuous PCO2 and pH monitoring.
Purpose of the Study:
- To evaluate the accuracy of the Paratrend 7 monitor for continuous PCO2 and pH measurements.
- To assess its performance when inserted into a peripheral vein in pediatric patients.
- To compare its readings against standard arterial blood gas (ABG) analysis.
Main Methods:
- A prospective case series was conducted in a pediatric intensive care unit.
- The Paratrend 7 system was inserted via a peripheral intravenous cannula.
- Continuous measurements were compared with intermittent arterial blood gas samples using linear regression and Bland-Altman analysis.
Main Results:
- Seventeen arterial blood gas samples were analyzed from four pediatric patients.
- The Paratrend 7 showed a strong correlation for pH (r² = 0.9367) and PCO2 (r² = 0.6845) compared to ABG.
- Bias ± precision was 3 ± 1.4 for PCO2 and 0.036 ± 0.02 for pH.
Conclusions:
- The Paratrend 7 monitor provides a clinically acceptable correlation with arterial PCO2 and pH values.
- This device may offer a viable option for continuous blood gas monitoring in pediatric respiratory failure.
- Further research could explore its long-term reliability and clinical utility.
Purpose:
To determine the accuracy of the Paratrend 7 monitor inserted into a peripheral vein in providing continuous measurements of PCO2 and pH in children with respiratory failure.
Methods:
In a prospective, case series at a University based PICU in a tertiary referral hospital and following informed consent, the Paratrend 7 intra-arterial blood gas monitoring system was inserted through a peripheral intravenous cannula. When clinically indicated, an arterial blood gas (ABG) was obtained. The values of pH and PCO2 from the Paratrend 7 and the ABG were compared using linear regression analysis and Bland-Altman analysis.
Results:
Seventeen ABGs were obtained in the 4 patients. PaC02 ranged from 29 to 51 mmHg and the pH values from 7.16 to 7.50. Linear regression analysis for the:Paratrend 7 pHvs the ABG pH resulted in an r = 0.9678 and an r(2) = 0.9367 (P < 0.0001). Linear regression analysis for the Paratrend 7 CO2 vs ABG CO2 resulted in an r = 0.8273 and an r(2) = 0.6845 (P = 0.01). Using a Bland and Altman analysis, the bias ± precision of the PCO2 values was 3 ± 1.4 and 0.036 ± 0.02 for the pH values.
Conclusion:
The pH and PCO2 values obtained from the Paratrend 7 monitor provide a clinically acceptable correlation with arterial values.
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