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Updated: Mar 16, 2026

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
Published on: June 28, 2019
Synthesis of C-18 mixed acid diacyl-sn-glycerol enantiomers
1Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada.
Abstract:
Procedures have been developed for the synthesis of both enantiomeric forms of mixed fatty acid, saturated and polyunsaturated 1,2-diacyl-sn-glycerols and 2,3-diacyl-sn-glycerols from D-mannitol as starting material. The following diacyl-sn-glycerols have been synthesized: 1-Stearoyl-2-linoleoyl-sn-glycerol, 1-stearoyl-2-linolenoyl-sn-glycerol, 2-linoleoyl-3-stearoyl-sn-glycerol and 2-linolenoyl-3-oleoyl-sn-glycerol. Their specific rotations, refractive indices, densities, solubilities, carbon and hydrogen analysis and iodine values have been reported.
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