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Nosocomial post-traumatic Rhizomucor soft tissue and bone infection treated with liposomial amphotericin B: case
M B Pasticci1, F Baldelli2, C Fiacca3
1Infectious Disease Section Department of Experimental Medicine and Biochemical Sciences, University of Perugia, I-06100, Perugia, Italy. pasticci@unipg.it.
Abstract:
Mucornycosis is a rare fungal infection most commonly occuring in patients with severe immunocompromise, diabetes, uremia or trauma. Only a few cases of non axial skeletal bone osteomyelitis have been reported. We report a case of nosocomial cellulitis and osteomyelitis complicating a posttraumatic bacterial infection, successfully treated with liposomial amphotericin B and surgical debridement. Traumatized patients with extensive tissue loss, receiving broad-spectrum antibiotics, can develop impaired immune responses and are at risk for fungal infections.
