Histiocytic chorioretinitis in a dog
Amanda B Sherman1, John M Cullen2, Hans D Westermeyer1
1Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
Veterinary Ophthalmology
|August 14, 2016
Summary
A dog
Area of Science:
- Veterinary ophthalmology
- Comparative pathology
Background:
- A canine patient presented with ocular abnormalities including bullous retinal detachment and choroidal thickening.
- Initial diagnostics suggested a neoplastic process in the right eye.
Observation:
- Subretinal cytology indicated atypical cell proliferation, leading to enucleation and a preliminary diagnosis of a benign choroidal melanocytic tumor.
- Six months later, the contralateral eye developed similar signs, responding positively to systemic steroids.
Findings:
- Immunohistochemistry (Melan-A, CD204) on the enucleated eye revised the diagnosis from a melanocytic tumor to histiocytic chorioretinitis.
- This revision underscores the diagnostic challenges in differentiating neoplastic from inflammatory conditions.
Implications:
- This case emphasizes the importance of advanced diagnostics like immunohistochemistry in veterinary pathology.
- Accurate differentiation between canine ocular neoplasia and inflammation is crucial for appropriate treatment and prognosis.
