Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.3K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.3K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.8K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.8K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

688
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
688

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Benralizumab is effective in severe asthma with CRS, regardless of demographic and clinical basal outcomes.

Allergologia et immunopathologia·2026
Same author

Cost-Effectiveness of Tezepelumab Versus Omalizumab in Patients with Severe Uncontrolled Allergic Asthma in Spain.

PharmacoEconomics - open·2026
Same author

Characteristics and clinical outcomes of patients with severe asthma receiving tezepelumab after marketing approval in Spain (T-ROSS II study): an observational study protocol.

BMJ open·2026
Same author

Rescue Inhaler Overuse in Severe Asthma: A Real-World Study of Short-Acting β<sub>2</sub>-Agonist and Short-Acting Muscarinic Antagonist Use.

Biomedicines·2026
Same author

EAACI Guidelines on Environmental Science for Allergy and Asthma-Evidence-Based Recommendations for Prevention and Public Health Action to Mitigate the Impact of Pollen Exposure on Respiratory Allergy.

Allergy·2026
Same author

Real-World Effectiveness of Tezepelumab Across T2 and Non-T2 Severe Asthma Phenotypes: A Multicenter Spanish Cohort Study.

Archivos de bronconeumologia·2026

Related Experiment Video

Updated: Mar 16, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
12:02

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Published on: May 2, 2018

13.1K

Biomarkers in Occupational Asthma.

Javier Dominguez-Ortega1,2, Pilar Barranco3,4, Rosa Rodríguez-Pérez3,4

  • 1Department of Allergy, La Paz Institute for Health Research (IdiPAZ), Hospital Universitario La Paz, Paseo de la Castellana, 261, 28046, Madrid, Spain. javier.dominguez@idipaz.es.

Current Allergy and Asthma Reports
|August 14, 2016
PubMed
Summary

Identifying biomarkers for occupational asthma is crucial. While airway inflammation markers are useful, specific signatures for various outcomes in work-related asthma remain elusive.

Keywords:
BiomarkersGenomic biomarkersOccupational asthmaWork-related asthma

More Related Videos

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.8K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

Related Experiment Videos

Last Updated: Mar 16, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
12:02

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Published on: May 2, 2018

13.1K
Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.8K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

Area of Science:

  • Allergy and immunology
  • Occupational medicine
  • Respiratory medicine

Background:

  • Work-related asthma is a prevalent condition in adults, triggered by workplace exposures.
  • Occupational asthma serves as a model for studying allergy and inflammation biomarkers.
  • Identifying reliable biomarkers is essential for understanding disease inception and progression.

Purpose of the Study:

  • To review the current understanding of biomarkers in occupational asthma.
  • To highlight the challenges in identifying specific markers for different outcomes.
  • To explore the potential of various approaches, including genetic studies, for biomarker discovery.

Main Methods:

  • Review of existing literature on occupational asthma biomarkers.
  • Discussion of specific inhalation challenge as a method for biomarker validation.
  • Exploration of blood-borne and local airway biomarkers.
  • Consideration of genetic and gene-environment interaction studies.

Main Results:

  • Airway inflammatory biomarkers have documented utility.
  • Specific biomarkers or signatures for distinct occupational asthma outcomes are not yet clearly defined.
  • Systemic and local biomarkers are being investigated.

Conclusions:

  • Despite research efforts, definitive biomarkers for occupational asthma outcomes remain elusive.
  • Further research is needed to identify specific inflammatory and genomic markers.
  • Occupational asthma research provides insights into broader allergy and inflammatory processes.