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Published on: April 21, 2022
Pleural effusion as a manifestation of multiple myeloma
Nousheen Iqbal1, Muhammad Usman Tariq2, Mohammad Usman Shaikh3
1Department of Pulmonary Medicine, Aga Khan Hospital, Karachi, Pakistan.
Abstract:
Multiple myeloma is a clonal B-cell malignancy, characterised by proliferation of plasma cells and secretion of paraproteins. These plasma cells accumulate predominantly in the bone marrow; rarely, they invade other areas, especially the thorax. Myeloma presenting with a pleural effusion is rare and reported in only 6% of patients with myeloma. Such patients generally present late and have a poor prognosis. Here, we describe a patient presenting with a lung mass, renal failure and a massive unilateral pleural effusion due to multiple myeloma who was treated successfully.
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