Related Experiment Video

Updated: Mar 16, 2026

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

14.9K

Adherence to Childhood Tuberculosis Treatment in Mozambique

Elisa Lopez-Varela1,2, Victor Guillermo Sequera1,3, Alberto L García-Basteiro1,2,4

  • 1ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat De Barcelona, Barcelona, Spain c/ Rosselló, 132, 5° 2 (08036).

Journal of Tropical Pediatrics
|August 14, 2016
PubMed

Insights

Adherence to tuberculosis (TB) treatment in children in Mozambique was assessed. Incomplete adherence was observed in 31.3% of cases, linked to malnutrition or having a migrant mother.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Limited literature exists on pediatric tuberculosis (TB) treatment adherence.
  • Tuberculosis remains a significant global health challenge, particularly in resource-limited settings.

Purpose of the Study:

  • To describe TB treatment outcomes in Mozambican children.
  • To evaluate factors associated with poor adherence to TB treatment in this population.

Main Methods:

  • A sub-study of a community TB incidence study involving children under 3 years old.
  • Incomplete adherence was defined as lost-to-follow-up or treatment delays exceeding 3 weeks.

Main Results:

  • Of 50 TB treatments assessed, 88% completed treatment successfully.
  • Incomplete adherence was found in 31.3% of cases (15/48).
  • Factors associated with incomplete adherence included malnutrition and a history of a migrant mother.

Conclusions:

  • Despite generally good treatment outcomes, a substantial proportion of children exhibited incomplete adherence.
  • Further research with larger pediatric TB cohorts and qualitative methods is necessary to confirm factors influencing non-adherence.
Abstract

Keywords:
adherencechildhoodtreatment.tuberculosis

More Related Videos

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.7K
An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

2.4K

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
737
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.2K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
617
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.9K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.3K
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
313