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Published on: February 28, 2025
Gallbladder disease in children
David H Rothstein1, Carroll M Harmon1
1Department of Pediatric Surgery, Women and Children׳s Hospital of Buffalo, 219 Bryant St, Buffalo, New York 14222; Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.
Insights
Pediatric biliary disease is increasing, linked to rising childhood obesity and more gallbladder removal surgeries. Surgeons face challenges diagnosing and treating gallbladder pain without stones, like biliary dyskinesia.
Area of Science:
- Pediatric Gastroenterology
- Surgical Management of Biliary Tract Disease
Background:
- Biliary disease incidence in children has significantly increased over recent decades.
- This rise correlates with increasing rates of pediatric obesity.
- Cholecystectomy rates in children have also seen a notable increase.
Purpose of the Study:
- To highlight the changing landscape of pediatric biliary disease.
- To discuss the diagnostic and therapeutic challenges posed by acalculous gallbladder conditions.
Main Methods:
- Review of recent trends in pediatric biliary disease.
- Analysis of factors contributing to increased incidence.
- Examination of challenges in diagnosing and managing biliary dyskinesia.
Main Results:
- A marked increase in pediatric biliary disease incidence.
- A parallel rise in pediatric obesity and cholecystectomy rates.
- Growing prevalence of acalculous gallbladder pain, including biliary dyskinesia.
Conclusions:
- Pediatric biliary disease patterns are shifting, with obesity as a likely driver.
- Acalculous gallbladder conditions present complex management issues for pediatric surgeons.
- Further research is needed to refine diagnostic and treatment strategies for these conditions.
Abstract:
Biliary disease in children has changed over the past few decades, with a marked rise in incidence-perhaps most related to the parallel rise in pediatric obesity-as well as a rise in cholecystectomy rates. In addition to stone disease (cholelithiasis), acalculous causes of gallbladder pain such as biliary dyskinesia, also appear to be on the rise and present diagnostic and treatment conundrums to surgeons.
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