Related Experiment Video
Updated: Mar 16, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Burkitt Lymphoma Preceded by Autoimmune Hemolytic Anemia due to Anti-D Antibody
Yoshimi Mizuno1, Yuji Shimura, Shigeo Horiike
1Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Japan.
Abstract:
We herein report a rare case of Burkitt lymphoma (BL) preceded by autoimmune hemolytic anemia (AIHA) caused by autoantibodies against D antigen. After a partial response to AIHA with prednisolone (PSL) treatment for 7 months, the patient developed BL with a t(8;22)(q24;q11.2) chromosomal translocation. Intensive immunochemotherapy, including rituximab, led to a complete response (CR) of BL; however, anti-D antibody remained detectable in the plasma and antibody-dissociated solution from erythrocytes, thus continuous therapy with PSL was necessary even after achievement of the CR. BL with AIHA is extremely rare, with only one previously reported case in the literature.
Related Concept Videos
Hypersensitivity Reactions: Cytolytic Reactions
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
Hybridoma Technology
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

