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Translocation 3;21 in Philadelphia chromosome positive chronic myeloid leukemia at diagnosis
1Department of Haematology, University of Wales College of Medicine, Cardiff, U.K.
Cancer Genetics and Cytogenetics
|June 1, 1989
Abstract:
We describe a further case of Philadelphia chromosome-positive chronic myeloid leukemia with a t(3;21)(q26.2;q22) present in the chronic phase. Blastic transformation occurred 8 months after presentation. The presence of the t(3;21) may indicate a poor prognosis.