Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

1.5K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.5K
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

689
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
689
Symbiosis00:58

Symbiosis

38.1K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
38.1K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.3K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.3K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.9K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.9K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.2K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9-Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Highly cross-reactive and competent effectors dominate the CD8+ T cell response in Trypanosoma cruzi infection.

Journal of immunology (Baltimore, Md. : 1950)·2025
Same author

The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease.

Current opinion in microbiology·2025
Same author

Serial 'deep-sampling' PCR of fragmented DNA reveals the wide range of <i>Trypanosoma cruzi</i> burden among chronically infected human, macaque, and canine hosts, and allows accurate monitoring of parasite load following treatment.

eLife·2025
Same author

Serial 'deep-sampling' PCR of fragmented DNA reveals the wide range of <i>Trypanosoma cruzi</i> burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment.

bioRxiv : the preprint server for biology·2024
Same author

Positive clinical outcome using a modified dosing regimen of benznidazole in dogs at high risk for infection or acutely infected with Trypanosoma cruzi.

Journal of veterinary internal medicine·2024

Related Experiment Video

Updated: Mar 16, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing &#946;-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

3.9K

Chagas Disease: A Solvable Problem, Ignored.

Rick L Tarleton1

  • 1Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA; The Chagas Disease Foundation, Athens, GA, USA(i).

Trends in Molecular Medicine
|August 16, 2016
PubMed
Summary

Chagas disease, a major parasitic threat in the Americas, is often overlooked and undertreated. This communication explores why this curable and manageable condition remains a global challenge and proposes solutions.

Keywords:
Chagas diseaseTrypanosoma cruzi.drug discoveryneglected diseases

More Related Videos

Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response
07:59

Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response

Published on: May 31, 2024

2.2K
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

15.8K

Related Experiment Videos

Last Updated: Mar 16, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing &#946;-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

3.9K
Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response
07:59

Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response

Published on: May 31, 2024

2.2K
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

15.8K

Area of Science:

  • Neglected tropical diseases
  • Parasitic infections
  • Public health in the Americas

Background:

  • Chagas disease is a significant parasitic illness impacting the Americas.
  • It is currently underdiagnosed and inadequately treated.
  • The infection is curable, and the disease burden is manageable.

Purpose of the Study:

  • To investigate the reasons behind the lack of awareness and treatment for Chagas disease.
  • To identify strategies for improving the management of this parasitic infection.
  • To highlight the curable nature and manageable scope of the Chagas disease problem.

Main Methods:

  • This communication is a review and analysis of the current situation.
  • It synthesizes existing knowledge on Chagas disease prevalence, diagnosis, and treatment barriers.
  • It proposes potential interventions and policy recommendations.

Main Results:

  • Several factors contribute to the underdiagnosis and undertreatment of Chagas disease.
  • Lack of awareness among the public and healthcare providers is a major issue.
  • Effective strategies can be implemented to improve disease control and patient outcomes.

Conclusions:

  • Chagas disease requires increased attention and integrated management strategies.
  • Addressing the knowledge gap and improving access to diagnosis and treatment are crucial.
  • Transforming the current situation is feasible, making Chagas disease a manageable global health problem.