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In-vitro anticancer activity of green synthesized silver nanoparticles on MCF-7 human breast cancer cells
Suk Ju Jang1, In Jun Yang1, Clement O Tettey1
1Department of Physiology, College of Korean Medicine, Dongguk University, Gyeongju 780-714, South Korea.
Abstract:
In recent years, green synthesis of metallic nanoparticles is a growing area of research because of their potential applications in nanomedicine. In the present study we synthesized silver nanoparticles (silver NPs) from AgNO3 using aqueous extract of Lonicera hypoglauca flower as reducing and capping agents. The synthesized silver NPs were characterized using UV-Vis spectroscopy, FTIR, SEM-ED, TEM and SAED. Silver NPs were found to be significantly toxic to MCF-7 cells via the induction of apoptosis whereas sparing normal immune system (RAW 264.7) cells.
