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Published on: September 22, 2023
Association between cancer and allergies
Renata Kozłowska1, Andrzej Bożek1, Jerzy Jarząb1
1Clinical Department of Internal Disease, Dermatology and Allergology in Zabrze, Medical University of Silesia, Katowice, Poland.
Patients with cancer showed a lower incidence of allergies, particularly allergic rhinitis. This suggests a potential link between atopy and cancer risk, warranting further investigation into allergy and cancer connections.
Area of Science:
- Immunology
- Oncology
- Epidemiology
Background:
- Global rise in allergies and cancer incidence.
- Hypothesis: Atopy (allergic predisposition) may influence cancer risk.
Purpose of the Study:
- To investigate the relationship between allergies and cancer.
- To compare allergy prevalence in cancer patients versus a control group.
Main Methods:
- Examined 1525 cancer patients for allergies.
- Retrospective analysis of allergy diagnostics.
- Included assessment for bronchial asthma and allergic rhinitis.
- Utilized a control group of non-cancer patients.
Main Results:
- Cancer patients had significantly lower IgE-mediated allergic diseases.
- Lower odds ratios observed for allergic rhinitis (0.67) and atopic dermatitis (0.89) in cancer patients.
- Mean serum total IgE levels were significantly lower in cancer patients (45.98 IU/l) compared to controls (83.2 IU/l).
Conclusions:
- Incidence of allergies, especially allergic rhinitis, is lower in patients with certain cancers.
- Findings suggest a potential inverse relationship between atopy and cancer.
- Further research is required to validate these observations.
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