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Mixed Adenoneuroendocrine Carcinoma Causing Colonic Intussusception
Marina Morais1, André Costa Pinho1, Ana Marques2
1Colorectal Unit, Department of Surgery, Sao João Medical Center, Faculty of Medicine, The University of Porto, 4200-319 Porto, Portugal.
Case Reports in Surgery
|August 16, 2016
Summary
Adult colonic intussusception, often caused by malignancy, requires early diagnosis. This case highlights a rare mixed adenoneuroendocrine carcinoma presenting as a large polyp in a 64-year-old male.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Colonic intussusception is an uncommon cause of intestinal obstruction in adults.
- Malignant lesions are implicated in approximately 70% of adult colonic intussusception cases.
- Timely diagnosis and intervention are critical for favorable patient outcomes.
Purpose of the Study:
- To report a rare case of right colonic intussusception in an adult.
- To highlight the diagnostic challenges posed by the rarity and nonspecific presentation of adult colonic intussusception.
- To describe a mixed adenoneuroendocrine carcinoma (MANEC) as the underlying cause of intussusception.
Main Methods:
- Case presentation of a 64-year-old male with right colonic intussusception.
- Description of the intussusception caused by a giant pedunculated polyp (54 mm).
- Surgical management involving right colectomy with primary anastomosis and adjuvant chemotherapy.
Main Results:
- The intussusception was successfully treated with right colectomy and anastomosis.
- Histopathological examination revealed a mixed adenoneuroendocrine carcinoma (MANEC) as the causative agent.
- The tumor presented as a large, 54 mm, pedunculated polyp.
Conclusions:
- Adult colonic intussusception diagnosis can be challenging due to its infrequent occurrence and vague symptoms.
- Mixed adenoneuroendocrine carcinoma (MANEC) represents a rare etiology for colonic intussusception in adults.
- This case underscores the importance of considering malignancy in adult intussusception, even with unusual presentations.
