Related Experiment Video
Updated: Mar 16, 2026

Establishment of Acute Pontine Infarction in Rats by Electrical Stimulation
Published on: August 27, 2020
"Salt and Pepper" Pontine Infarct
Lance J Lyons1, Susan W Law, John L Kubie
1SUNY Downstate College of Medicine (LJL), Brooklyn, New York; Department of Neurology and Stroke Center (SWL), SUNY Downstate Medical Center, Brooklyn, New York; Department of Cell Biology (JLK), SUNY Downstate Medical Center, Brooklyn, New York.
Abstract:
A paramedian pontine stroke may herald the unique symptom of "salt and pepper" eye pain, in which patients describe the sensation of pepper rubbed into the eye. While localization of the lesion is a common thread among published cases, the mechanism for the sensation of eye pain is still a matter of conjecture. It is important for clinicians to be aware of this unique symptom because strokes rarely present with eye pain and failure to establish this diagnosis might lead to a poor clinical outcome.
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Olfactory Receptors: Location and Structure

