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Related Concept Videos

Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

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The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
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Parental Care00:55

Parental Care

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Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
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Diencephalon: Hypothalamus and Coordination01:23

Diencephalon: Hypothalamus and Coordination

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The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
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Neurotransmitters01:31

Neurotransmitters

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Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
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Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:27

Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla

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The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
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Diencephalon: Anatomical Regions01:30

Diencephalon: Anatomical Regions

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The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the...
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Related Experiment Video

Updated: Mar 16, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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The subcortical maternal complex: multiple functions for one biological structure?

D Bebbere1, L Masala2, D F Albertini3,4

  • 1Department of Veterinary Medicine, University of Sassari, via Vienna 2, 07100, Sassari, Italy. dbebbere@uniss.it.

Journal of Assisted Reproduction and Genetics
|August 16, 2016
PubMed
Summary
This summary is machine-generated.

The subcortical maternal complex (SCMC) is crucial for early embryonic development in mammals. Further research is needed to fully understand its functions and potential role in human fertility.

Keywords:
Developmental competenceKHDC3/FILIANLRP5/MATEROOEP/FLOPEDOocyteTLE6

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Area of Science:

  • Reproductive biology
  • Developmental biology
  • Molecular genetics

Background:

  • The subcortical maternal complex (SCMC) is a unique multiprotein complex found in mammalian oocytes and early embryos.
  • SCMC is essential for the zygote to progress beyond initial cell divisions.
  • The precise physiological functions of SCMC, like other maternal effect genes, are not fully understood.

Purpose of the Study:

  • To review recent findings on the subcortical maternal complex (SCMC).
  • To discuss the potential physiological roles of SCMC.
  • To stimulate future research directions regarding SCMC.

Main Methods:

  • This mini-review synthesizes recent scientific literature.
  • It analyzes molecular insights into SCMC functions.
  • It discusses the implications of SCMC in mammalian reproduction.

Main Results:

  • Recent evidence offers molecular insights into potential SCMC functions.
  • SCMC's role in early embryonic cell division is established.
  • Growing interest exists in SCMC's connection to human fertility.

Conclusions:

  • The complete physiological role of SCMC requires further elucidation.
  • Understanding SCMC is critical for advancing reproductive science.
  • Future research should explore SCMC's mechanisms and fertility implications.