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Updated: Mar 16, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

3D Printed Multimaterial Microfluidic Valve.

Steven J Keating¹, Maria Isabella Gariboldi¹, William G Patrick¹

¹Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

|August 16, 2016

Summary

This summary is machine-generated.

We developed a novel 3D printed multimaterial microfluidic proportional valve. This innovation enables precise fluid control in programmable devices, advancing applications in DNA analysis and soft robotics.

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Area of Science:

Engineering
Materials Science
Microfluidics

Background:

Microfluidic valves are essential for automated fluid control in lab-on-a-chip devices.
Existing 3D printed valves often lack the necessary flexibility and programmability for complex applications.
Developing integrated, multi-property fluidic components is crucial for next-generation devices.

Purpose of the Study:

To introduce a novel 3D printed multimaterial microfluidic proportional valve.
To characterize the performance of these new valves.
To explore design variations for optimizing valve properties.

Main Methods:

Utilizing 3D printing with multiple materials (stiff and flexible) to create microfluidic valves.
Spatially constraining fluidic deformation through material combinations.
Investigating the impact of channel width, membrane thickness, and membrane stiffness on valve performance.

Main Results:

Demonstrated a functional multimaterial microfluidic proportional valve with enhanced control capabilities.
Characterized valve performance, including pressure-flow relationships and actuation response.
Explored design variations showing potential for tunable stiffness and geometry.

Conclusions:

The novel multimaterial valve design enables precise, programmable fluid control in a single printing step.
This technology facilitates the creation of functionally graded devices with integrated valves.
Potential applications include DNA assembly, continuous sensing, and soft robotics.