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Updated: Mar 16, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Dual-Emissive Platinum(II) Metallacycles with Thiophene-Containing Bisacetylide Ligands
Yang Cao1, Michael O Wolf1, Brian O Patrick1
1Department of Chemistry, 2036 Main Mall, University of British Columbia , Vancouver, British Columbia V6T 1Z1, Canada.
Abstract:
Three cis-diphosphino Pt(II) metallacycles with thiophene-containing bisacetylide ligands were synthesized and their absorption and emission properties examined. These properties are explained by DFT and TD-DFT analysis of ground-state as well as singlet- and triplet-state energies and geometries. Two of the metallacycles show room-temperature dual emission (fluorescence and phosphorescence) with different intensity ratios. Replacing the phenylene or ethynylene groups with thiophene rings in the bisacetylide ligand of the metallacycles results in modulation of the S1 and T1 states to show stronger fluorescence and weaker phosphorescence. More rigid and planar metallacycles suffer less from energy loss due to smaller degrees of structural reorganization and thermal deactivation. These are important factors to consider when designing single-component dual-emissive materials for applications such as white-emitting OLEDs, self-referencing oxygen sensors, and hypoxia contrast agents.
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