Related Experiment Video
Updated: Mar 16, 2026
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
Refractive shift of silicone oil tamponade in pseudophakic eye
Wei Fang1, Jiuke Li1, Xiaohong Jin1
1Ophthalmology Department of SIR RUN RUN SHAW hospital, SIR RUN RUN SHAW Institute of Clinical Medicine of Zhejiang University, #3 Qingchun East Road, Hangzhou, Zhejiang, 310016, People's Republic of China.
Background:
Refraction change of silicone oil (SO) tamponade in phakic and aphakic eye has been studied thoroughly; however, it is rarely studied in pseudophakic eye. In this paper we aimed to deduce a theoretical formula predicting refractive shift of silicone oil tamponade in pseudophakic eye and compared it with clinical findings.
Method:
A theoretical formula was deduced through strict geometric optical principles under the Helmholtz Schematic eye model. Pre/postoperative refractive status of patients who previously underwent phacoemulsification, intraocular lens (IOL) implant, vitrectomy, SO tamponade and required SO extraction was studied.
Results:
Twenty-six patients (27 eyes, 13 males and 13 females) were studied. Refractive error of SO-off was -1.88 ± 2.73D, and of SO-in was 2.02 ± 3.90. Refractive shift of SO tamponade was -3.90 ± 1.74D. Refractive shift was significantly associated with refractive power of IOL (r = -0.7903, p < 0.0001, Pearson correlation test) and anterior chamber distance (ACD, r = 0.3840, p = 0.0480, Pearson correlation test). Theoretical refractive shift was -4.10 ± 1.51D, and there was no significant difference between the theoretical and the clinical refractive shift (p = 0.3329, Paired T test).
Conclusions:
Refractive shift of SO tamponade in pseudophakic eye correlates with refractive power of implanted IOL and ACD, and strong correlation between theoretical formula and clinical findings was detected.
