Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

First Law: Particles in Two-dimensional Equilibrium01:18

First Law: Particles in Two-dimensional Equilibrium

16.9K
Recall that a particle in equilibrium is one for which the external forces are balanced. Static equilibrium involves objects at rest, and dynamic equilibrium involves objects in motion without acceleration; but it is important to remember that these conditions are relative. For instance, an object may be at rest when viewed from one frame of reference, but that same object would appear to be in motion when viewed by someone moving at a constant velocity.
Newton's first law tells us about...
16.9K
Three-Dimensional Force System:Problem Solving01:30

Three-Dimensional Force System:Problem Solving

1.4K
A three-dimensional force system refers to a scenario in which three forces act simultaneously in three different directions. This type of problem is commonly encountered in physics and engineering, where it is necessary to calculate the resultant force on the system, which can then be used to predict or analyze the behavior of the object or structure under consideration.
To solve a three-dimensional force system, first resolve each force into its respective scalar components. Do this using...
1.4K
Two-Dimensional Force System: Problem Solving01:29

Two-Dimensional Force System: Problem Solving

1.4K
Solving problems related to two-dimensional force systems is an essential aspect of mechanics and engineering. By applying the principles of vector analysis and force equilibrium, one can determine the effect of multiple forces acting on an object in a two-dimensional space.
The first step to solving a two-dimensional force system problem is to draw a free-body diagram of the object under consideration. This diagram helps identify all the external forces acting on the object, including their...
1.4K
Equations of Motion: Rectangular Coordinates and Cylindrical Coordinates01:21

Equations of Motion: Rectangular Coordinates and Cylindrical Coordinates

832
Understanding the motion of particles is a fundamental aspect of classical mechanics, and the choice of the coordinate system plays a pivotal role in unraveling the complexities of their dynamics.
When a particle moves relative to an inertial frame, the equations of motion can be expressed using rectangular components. If the motion is confined to the x-y plane, the equations having the x and y coordinates only can be used to simplify the mathematical representation.
However, when particles...
832
Three-Dimensional Force System01:30

Three-Dimensional Force System

3.0K
In mechanical engineering, a three-dimensional force system is a system of forces acting in three dimensions, with forces applied along the x, y, and z coordinate axes. The three-dimensional force system is an important concept in mechanical engineering, as it allows engineers to understand and analyze the behavior of objects and structures in three dimensions. By understanding the forces acting on a system, engineers can design more efficient and effective mechanical systems that can withstand...
3.0K
First Law: Particles in One-dimensional Equilibrium01:10

First Law: Particles in One-dimensional Equilibrium

8.3K
Newton's first law of motion states that a body at rest remains at rest, or if in motion, remains in motion at constant velocity, unless acted on by a net external force. It also states that there must be a cause for any change in velocity (a change in either magnitude or direction) to occur. This cause is a net external force. For example, consider what happens to an object sliding along a rough horizontal surface. The object quickly grinds to a halt, due to the net force of friction. If...
8.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness and safety analysis of initial treatment with belimumab in childhood-onset systemic lupus erythematosus.

Frontiers in immunology·2026
Same author

Identification and Quantitation of Cardiac Hypertrophy Inhibitory Components in Trichosanthis Pericarpium Injection Based on UHPLC-QE-MS and Spectrum-Effect Relationships.

Biomedical chromatography : BMC·2026
Same author

Development of functional cheese sticks using konjac glucomannan: regulated pickering double emulsions under different heat treatments.

Food chemistry: X·2026
Same author

Pattern Formation During Swelling in Aqueous Glycerin Solutions of Hydrogel Beads.

The journal of physical chemistry. B·2026
Same author

HSPH1 and DNAJB1 as potential key regulators in hepatic ischemia-reperfusion injury.

Molecular immunology·2026
Same author

Salvianolic acid A reduces lipotoxicity injury of cardiomyocytes by orchestrating oxidative stress and inflammation via Akt/Nrf2/NF-κB axis.

Journal of molecular histology·2025
Same journal

Therapeutic potential of crude protein extracts from two Egyptian freshwater snails Lanistes carinatus and Bellamya unicolor.

Scientific reports·2026
Same journal

Microbial contamination of donor corneas and post-keratoplasty endophthalmitis: a comparison between Japanese and U.S. eye banks using cold storage.

Scientific reports·2026
Same journal

Prevalence and contributing factors of virological non-suppression among adult patients on first-line antiretroviral therapy in tertiary hospitals in Ethiopia.

Scientific reports·2026
Same journal

An in vitro comparison of color stability between alkasite and different restorative materials in various staining solutions.

Scientific reports·2026
Same journal

Toward accessible mRNA LNP formulation: systematic evaluation of mixing strategies and key parameters.

Scientific reports·2026
Same journal

A network analysis of personality traits, mentalizing, and psychological health in Chinese college students.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Mar 16, 2026

Image-based Lagrangian Particle Tracking in Bed-load Experiments
10:32

Image-based Lagrangian Particle Tracking in Bed-load Experiments

Published on: July 20, 2017

9.6K

Gravity driven deterministic lateral displacement for suspended particles in a 3D obstacle array.

Siqi Du1, German Drazer1

  • 1Mechanical and Aerospace Engineering Department, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

Scientific Reports
|August 17, 2016
PubMed
Summary
This summary is machine-generated.

Deterministic lateral displacement (DLD) systems achieve enhanced particle separation by utilizing 3D trajectories. This method enables size-dependent fractionation of polydisperse suspensions into multiple streams.

More Related Videos

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

9.2K
Methods for Measuring the Orientation and Rotation Rate of 3D-printed Particles in Turbulence
12:34

Methods for Measuring the Orientation and Rotation Rate of 3D-printed Particles in Turbulence

Published on: June 24, 2016

10.6K

Related Experiment Videos

Last Updated: Mar 16, 2026

Image-based Lagrangian Particle Tracking in Bed-load Experiments
10:32

Image-based Lagrangian Particle Tracking in Bed-load Experiments

Published on: July 20, 2017

9.6K
Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

9.2K
Methods for Measuring the Orientation and Rotation Rate of 3D-printed Particles in Turbulence
12:34

Methods for Measuring the Orientation and Rotation Rate of 3D-printed Particles in Turbulence

Published on: June 24, 2016

10.6K

Area of Science:

  • Microfluidics
  • Biophysics
  • Particle Separation

Background:

  • Deterministic Lateral Displacement (DLD) systems are widely used for particle separation.
  • Traditional 2D DLD systems exhibit limitations in separation resolution.
  • Expanding DLD to three dimensions offers potential for enhanced performance.

Purpose of the Study:

  • To enhance the separation capabilities of DLD systems.
  • To investigate the effect of three-dimensional particle trajectories on separation.
  • To achieve size-dependent fractionation of polydisperse suspensions.

Main Methods:

  • Modification of DLD systems to induce three-dimensional particle motion.
  • Utilizing arrays of long cylindrical posts to guide particles.
  • Analyzing both in-plane and out-of-plane particle trajectories.
  • Applying a theoretical model for force-driven 2D DLD systems.

Main Results:

  • Particles exhibit size-dependent out-of-plane motion.
  • In-plane motion is analogous to traditional 2D DLD systems.
  • A theoretical model accurately describes the observed in-plane motion.
  • Simultaneous fractionation of polydisperse suspensions into multiple streams is achieved.

Conclusions:

  • Three-dimensional DLD significantly enhances particle separation ability.
  • Exploiting both in-plane and out-of-plane motion enables precise fractionation.
  • This modified DLD approach offers a powerful tool for microfluidic applications.