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In Vitro Activity of Isavuconazole against Rasamsonia Species
J Steinmann1, S Dittmer2, J Houbraken3
1Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany Joerg.Steinmann@uk-essen.de.
Abstract:
The in vitro susceptibilities to the novel triazole isavuconazole and six other antifungal agents of a large collection of Rasamsonia isolates (n = 47) belonging to seven species were determined. Isavuconazole and voriconazole had no in vitro activity (MIC, >32 mg/liter) against isolates of the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all of the isolates tested (minimum effective concentration, ≤0.19 mg/liter).
