Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

3.0K
3.0K
Cancer Prevention02:59

Cancer Prevention

8.6K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.6K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.1K
Cancer Survival Analysis01:21

Cancer Survival Analysis

811
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
811
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

609
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
609
Cancer Vaccines01:30

Cancer Vaccines

1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[French clinical practice guidelines for the diagnosis and management of lung disease with alpha 1-antitrypsin deficiency].

Revue des maladies respiratoires·2022
Same author

Is COVID-19 pneumonia differentiable from other viral pneumonia on CT scan?

Respiratory medicine and research·2021
Same author

[Recommendations of French specialists on screening for lung cancer].

Revue des maladies respiratoires·2021
Same author

Artificial intelligence: from challenges to clinical implementation.

Diagnostic and interventional imaging·2020
Same author

Artificial intelligence solution to classify pulmonary nodules on CT.

Diagnostic and interventional imaging·2020
Same author

Lung cavitation in COVID-19 pneumonia.

Diagnostic and interventional imaging·2020

Related Experiment Video

Updated: Mar 16, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

16.3K

Lung cancer screening: Current status and perspective.

G Chassagnon1, M-P Revel1

  • 1Radiology department, Cochin Hospital, Paris Descartes University, 75004 Paris, France.

Diagnostic and Interventional Imaging
|August 17, 2016
PubMed
Summary

Low-dose computed tomography (CT) screening reduces lung cancer deaths by 20%. Expert radiologists and advanced techniques like volumetry can improve accuracy and minimize overdiagnosis risks for lung cancer patients.

Keywords:
Computed tomographyLungLung cancerScreening

More Related Videos

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

500

Related Experiment Videos

Last Updated: Mar 16, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

16.3K
Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

500

Area of Science:

  • Pulmonology
  • Radiology
  • Oncology

Background:

  • Lung cancer screening using low-dose computed tomography (CT) significantly reduces lung cancer-related mortality by 20% as demonstrated in the National Lung Screening Trial (NLST).
  • Effective dose for low-dose CT protocols should not exceed 1.5 mSv.
  • Radiologist expertise is crucial for accurate interpretation of screening scans.

Purpose of the Study:

  • To evaluate the effectiveness of low-dose CT screening in reducing lung cancer mortality.
  • To discuss methods for optimizing screening protocols and minimizing harms.
  • To explore future directions for improving lung cancer screening accuracy.

Main Methods:

  • Review of findings from the National Lung Screening Trial (NLST).
  • Discussion of low-dose CT acquisition protocols and dose limits.
  • Introduction of volumetry-based approaches, similar to the NELSON study, to reduce positive screening rates.
  • Consideration of overdiagnosis as a major harm of screening.

Main Results:

  • Low-dose CT screening reduces lung cancer mortality by 20%.
  • Volumetry-based approaches can decrease the rate of positive screens by approximately 2%.
  • Overdiagnosis of indolent tumors remains a significant concern.

Conclusions:

  • Low-dose CT is an effective tool for reducing lung cancer mortality.
  • Optimized protocols, expert interpretation, and advanced techniques like volumetry are essential for effective screening.
  • Biomarker research holds promise for enhancing the accuracy of lung cancer screening when combined with imaging.