Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Left ventricular function during stable sustained ventricular tachycardia. Hemodynamic and echo-Doppler analysis.

S B Baron1, S K Huang, K A Comess

  • 1Section of Cardiology, University of Arizona Medical Center, Tucson.

Chest
|August 1, 1989
PubMed
Summary

Sustained ventricular tachycardia (VT) significantly impairs left ventricular diastolic filling, leading to hemodynamic instability. Systolic function and valve regurgitation remain largely unchanged during VT.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The clinical value of multi-target stool fecal immunochemical test-DNA in early screening and diagnosis for colorectal cancer].

Zhonghua yi xue za zhi·2022
Same author

[Clinical application value of combined detection of serum miR-378 and miR-21 in gastric cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2018
Same author

Low yield of clinically significant transesophageal echocardiographic findings in patients with lacunar stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Optimization of the Hewlett-Packard particle-beam liquid chromatography-mass spectrometry interface by statistical experimental design.

Journal of the American Society for Mass Spectrometry·2013
Same author

Optimization of the atmospheric pressure chemical ionization liquid chromatography mass spectrometry interface.

Journal of the American Society for Mass Spectrometry·2013
Same author

Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.

Cell death & disease·2013

Area of Science:

  • Cardiology
  • Cardiovascular Physiology

Background:

  • Ventricular tachycardia (VT) can cause significant hemodynamic compromise.
  • Understanding the specific impact of VT on left ventricular (LV) function is crucial for patient management.

Purpose of the Study:

  • To evaluate the effects of sustained stable monomorphic ventricular tachycardia on left ventricular function.
  • To differentiate the contributions of systolic versus diastolic dysfunction and valvular regurgitation to hemodynamic changes during VT.

Main Methods:

  • Simultaneous echo-Doppler and hemodynamic monitoring were performed in ten patients during sinus rhythm and induced VT.
  • Key hemodynamic parameters including cardiac index, blood pressure, and filling pressures were measured.
  • LV diastolic filling was assessed using echo-Doppler parameters like inflow tract velocities and time velocity integrals.

Related Experiment Videos

Main Results:

  • Cardiac index and systolic blood pressure significantly decreased during VT.
  • Pulmonary artery wedge pressure increased, indicating elevated LV filling pressures.
  • Left ventricular ejection fraction and valvular regurgitation showed no significant changes.
  • Measures of LV diastolic filling, including maximal inflow tract velocities and time velocity integrals, were significantly reduced during VT.

Conclusions:

  • Hemodynamic deterioration during sustained VT is primarily attributed to impaired left ventricular diastolic filling.
  • Systolic LV function and valvular regurgitation do not appear to be major contributors to these hemodynamic changes.
  • Targeting diastolic dysfunction may be important in managing patients with VT.