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A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
First Described Case of Group B Streptococcus Pelvic Abscess in a Patient with No Medical Comorbidities
Paul Tyan1, Elias Abi-Khalil1, Karthik Dwarki2
1Department of Obstetrics and Gynecology, George Washington University, Washington, DC 20037, USA.
Insights
Group B Streptococcus (GBS) can cause invasive infections, like large pelvic abscesses, even in non-pregnant adults without underlying conditions. Prompt diagnosis and treatment with antibiotics and image-guided drainage are crucial for successful outcomes.
Area of Science:
- Infectious Diseases
- Microbiology
- Radiology
Background:
- Group B Streptococcus (GBS) typically affects neonates, pregnant women, and immunocompromised adults.
- GBS is an opportunistic pathogen with a broad host range.
- Invasive GBS infections are less common in non-pregnant, otherwise healthy adults.
Purpose of the Study:
- To report a rare case of a large pelvic abscess caused by Group B Streptococcus in a non-pregnant patient without comorbidities.
- To highlight the importance of considering GBS in the differential diagnosis of abscesses in diverse patient populations.
- To emphasize the successful management of such infections.
Main Methods:
- Interventional radiology (IR) guided drainage of the pelvic abscess.
- Administration of appropriate antibiotic therapy.
- Microbiological analysis to identify the causative organism.
Main Results:
- Successful treatment of a large pelvic abscess caused by Group B Streptococcus.
- The patient, a non-pregnant adult without underlying medical conditions, recovered fully.
- Image-guided drainage and targeted antibiotics proved effective.
Conclusions:
- Group B Streptococcus can cause severe, invasive infections, such as large pelvic abscesses, in non-pregnant individuals without comorbidities.
- Empirical antibiotic coverage for GBS should be considered in patients presenting with abscesses, regardless of traditional risk factors.
- Interventional radiology plays a key role in the management of complex abscesses.
Abstract:
Background. Group B Streptococcus is an organism that commonly infects a wide range of hosts including infants in the first week of life, pregnant women, and older age adults as well as adults with underlying medical comorbidities. Case. Large pelvic abscess in a nonpregnant patient found to be caused by Group B Streptococcus was treated successfully with IR guided drainage and antibiotics. Conclusion. Though rare, GBS can still be a cause of invasive infection even in individuals who are nonpregnant and have no underlying comorbidities. Empiric antibiotic coverage for this organism should be kept in mind when treating an abscess.
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