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Mesenteric Panniculitis (MP) in CT - A Predictor of Malignancy?
F Scheer1, P Spunar2, P Wiggermann3
1Institute of Diagnostic and Interventional Radiology/Neuroradiology, Westkuestenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg, Heide, Germany.
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|August 17, 2016
Summary
Mesenteric panniculitis (MP) is a condition that may indicate a higher risk of malignancy. This study found that MP is five times more likely to occur in patients with cancer, particularly non-Hodgkin lymphoma.
Area of Science:
- Radiology
- Oncology
- Gastroenterology
Background:
- The etiology of mesenteric panniculitis (MP) remains unclear, with various potential causes debated.
- Understanding the association between MP and malignancy is crucial for patient diagnosis and management.
Purpose of the Study:
- To retrospectively evaluate the correlation between mesenteric panniculitis (MP) and the presence of malignancy.
- To determine if MP serves as a predictor for underlying cancer.
Main Methods:
- A retrospective analysis of 5595 CT abdomen examinations over three years was conducted.
- Mesenteric panniculitis (MP) diagnosis required at least three of five specific CT signs.
- The study cohort included patients with and without confirmed cancer.
Main Results:
- Mesenteric panniculitis (MP) was diagnosed in 2.55% of patients.
- Malignancy was confirmed in 74.8% of MP cases.
- The prevalence of MP was significantly higher in patients with cancer (5.42%) compared to those without.
- Non-Hodgkin lymphoma showed the highest association with MP (22.6% of MP cases).
Conclusions:
- The presence of mesenteric panniculitis (MP) increases the risk of malignancy approximately fivefold.
- Mesenteric panniculitis (MP) frequently co-occurs with non-Hodgkin lymphoma.
- Typical CT findings allow for MP diagnosis, but differentiation from other mesenteric diseases is essential.
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