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Mesenteric Panniculitis (MP) in CT - A Predictor of Malignancy?

F Scheer1, P Spunar2, P Wiggermann3

  • 1Institute of Diagnostic and Interventional Radiology/Neuroradiology, Westkuestenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg, Heide, Germany.

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|August 17, 2016
PubMed
Abstract

Insights

Mesenteric panniculitis (MP) is a condition that may indicate a higher risk of malignancy. This study found that MP is five times more likely to occur in patients with cancer, particularly non-Hodgkin lymphoma.

Area of Science:

  • Radiology
  • Oncology
  • Gastroenterology

Background:

  • The etiology of mesenteric panniculitis (MP) remains unclear, with various potential causes debated.
  • Understanding the association between MP and malignancy is crucial for patient diagnosis and management.

Purpose of the Study:

  • To retrospectively evaluate the correlation between mesenteric panniculitis (MP) and the presence of malignancy.
  • To determine if MP serves as a predictor for underlying cancer.

Main Methods:

  • A retrospective analysis of 5595 CT abdomen examinations over three years was conducted.
  • Mesenteric panniculitis (MP) diagnosis required at least three of five specific CT signs.
  • The study cohort included patients with and without confirmed cancer.

Main Results:

  • Mesenteric panniculitis (MP) was diagnosed in 2.55% of patients.
  • Malignancy was confirmed in 74.8% of MP cases.
  • The prevalence of MP was significantly higher in patients with cancer (5.42%) compared to those without.
  • Non-Hodgkin lymphoma showed the highest association with MP (22.6% of MP cases).

Conclusions:

  • The presence of mesenteric panniculitis (MP) increases the risk of malignancy approximately fivefold.
  • Mesenteric panniculitis (MP) frequently co-occurs with non-Hodgkin lymphoma.
  • Typical CT findings allow for MP diagnosis, but differentiation from other mesenteric diseases is essential.

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