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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant III: Nursing Management01:16

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Acute Kidney Injury III: Clinical Manifestations01:29

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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A Kidney Transplant Recipient With Coronavirus Disease 2019: Utility of a Prognostication Score.

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The effect of peri-transplant plasmapheresis in the prevention of recurrent FSGS.

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Long-Term Non-End-Stage Renal Disease Risks After Living Kidney Donation.

A J Matas1, R E Hays2, H N Ibrahim3

  • 1Department of Surgery, University of Minnesota, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|August 17, 2016
PubMed
Summary

Living kidney donors face medical and psychosocial risks beyond end-stage renal disease (ESRD). More research is needed to quantify these risks and support donor well-being.

Keywords:
clinical research/practicedonors and donationdonors and donation: donor follow-updonors and donation: livinghealth services and outcomes researchkidney transplantation/nephrology

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Area of Science:

  • Nephrology
  • Transplant Surgery
  • Psychosocial Medicine

Background:

  • Living kidney donation generally yields positive outcomes and high donor satisfaction.
  • However, living kidney donors are susceptible to medical and psychosocial complications post-donation.

Purpose of the Study:

  • To review and summarize non-end-stage renal disease (ESRD) risks for living kidney donors.
  • To identify limitations in current data regarding donor outcomes.
  • To highlight areas for improved donor care and financial support.

Main Methods:

  • Systematic review of existing literature on medical and psychosocial risks.
  • Analysis of data limitations, including retrospective study designs and small sample sizes.
  • Discussion of differential risks among donor subsets and impact of postdonation events.

Main Results:

  • Non-ESRD medical risks (cardiovascular disease, mortality, preeclampsia) and psychosocial risks (mood disturbance, financial burden) are significant.
  • Current data often overshadows non-ESRD risks and lacks quantification of donation's true impact.
  • Postdonation events like diabetes and hypertension can be predicted and their adverse associations quantified.

Conclusions:

  • There is an imbalance in focusing on ESRD risk, neglecting other significant donor risks.
  • Improved systems are needed for evaluating and managing donors experiencing medical or psychosocial problems.
  • Addressing the financial burden on donors to make donation financially neutral should be a priority.