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Analysis of Complications in Outpatient ICD Surgery On or Off Warfarin Anticoagulation
Aneesh Tolat1, Aniruddha Singh2, Melissa Woiciechowski2
1Hoffman Heart and Vascular Institute, Saint Francis Hospital and Medical Center, University of Connecticut School of Medicine, Hartford., Connecticut. atolat@ctheartbeat.com.
Insights
Outpatient implantable cardioverter defibrillator (ICD) surgery is safe for patients on warfarin anticoagulation, with comparable overall complication rates. However, warfarin increases the risk of pocket hematoma during ICD procedures.
Area of Science:
- Cardiology
- Medical Devices
- Surgical Procedures
Background:
- Implantable cardioverter defibrillator (ICD) implantation practices vary, with some centers performing same-day discharge and others overnight stays.
- Many centers now perform ICD surgery on patients taking warfarin anticoagulation.
- Limited data exists on the safety of outpatient ICD surgery for anticoagulated patients.
Purpose of the Study:
- To evaluate the safety of outpatient ICD surgery in patients on warfarin anticoagulation compared to those not on anticoagulation.
- To assess procedural and 30-day complication rates in both groups.
Main Methods:
- A retrospective study of 866 patients undergoing outpatient ICD surgery from April 2010 to September 2014.
- Patients on novel oral anticoagulants or without a recent INR were excluded.
- Patients were divided into two groups: warfarin anticoagulated (n=230) and non-anticoagulated (n=518).
Main Results:
- Overall 30-day complication rates were similar between the warfarin group (4.3%) and the non-anticoagulated group (2.9%), with no significant difference (P=0.31).
- The pocket hematoma rate was significantly higher in the warfarin group (3.5%) compared to the non-anticoagulated group (0.4%) (P=0.001).
Conclusions:
- Outpatient ICD surgery demonstrates low complication rates, whether patients are on or off warfarin anticoagulation.
- Warfarin use during outpatient ICD surgery is associated with a higher incidence of pocket hematoma.
- These findings support the safety of outpatient ICD procedures but highlight the increased risk of hematoma in patients on warfarin.
Background:
Implantable cardioverter defibrillator (ICD) implantation is being performed differently at many hospitals, with some keeping patients overnight after procedure while others discharge patients home same day. In addition, many centers are now performing ICD surgery while on warfarin anticoagulation. There are, however, limited data on outpatient ICD surgery on anticoagulated (AC) patients.
Objective:
We wished to evaluate the safety of performing outpatient ICD surgery with and without warfarin anticoagulation.
Methods:
We evaluated 866 patients who underwent outpatient ICD surgery between April 2010 and September 2014. Patients who were on novel oral anticoagulants, or did not have an international normalized ratio drawn within 24 hours of the procedure were excluded and the remainder were divided into two groups based on whether they were on (n = 230) or off (n = 518) warfarin anticoagulation. We evaluated both procedural and 30-day complications in both groups.
Results:
The complication rate at 30 days in the warfarin AC group was 4.3%, while in the nonanticoagulated (NAC) group was 2.9% and not significantly different (P = 0.31). However, the pocket hematoma rate in the warfarin anticoagulated group was 3.5%, as compared to the NAC group that was 0.4% (P = 0.001).
Conclusion:
Complications from ICD surgery are low in the ambulatory setting on or off warfarin anticoagulation and appear to be comparable. However, warfarin use during ICD surgery is associated with an increased risk of pocket hematoma.
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