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Published on: September 22, 2020
Outcomes in Critical Limb Ischemia Compared by Distance from Referral Center
Peter B Bartline1, Bjoern D Suckow2, Benjamin S Brooke1
1Division of Vascular Surgery, University of Utah School of Medicine, Salt Lake City, UT.
Insights
Patients traveling longer distances for critical limb ischemia (CLI) revascularization had better amputation-free survival (AFS). Referral distance did not negatively impact outcomes or long-term follow-up for CLI patients.
Area of Science:
- Vascular Surgery
- Health Services Research
Background:
- Limited data exist on how referral distance affects outcomes for critical limb ischemia (CLI) patients undergoing revascularization.
- This study investigated the assumption that longer travel distances correlate with worse outcomes.
Purpose of the Study:
- To evaluate the impact of referral distance on revascularization outcomes in patients with CLI.
- To determine if patients traveling over 100 miles experience different results compared to those closer to the treatment center.
Main Methods:
- Retrospective cohort analysis of 300 CLI patients undergoing revascularization from 2000-2010.
- Patients were grouped by referral distance (>100 miles vs. <100 miles).
- Outcomes analyzed included length of stay, functional status, disposition, follow-up, and amputation-free survival (AFS) using Cox models.
Main Results:
- Patients traveling >100 miles had superior 5-year AFS (73% vs. 56%, P=0.02).
- Referral distance did not significantly affect length of stay, functional status, or discharge disposition.
- Long-term follow-up was similar between groups; longer distance was independently associated with improved AFS.
Conclusions:
- Referral distance does not adversely affect amputation-free survival or long-term follow-up in CLI patients.
- Patients from rural settings seeking revascularization at tertiary centers can expect comparable outcomes to those living nearer.
Background:
Little data exist regarding the effect of referral distance on outcomes after revascularization for critical limb ischemia (CLI). We tested the assumption that patients who travel longer distances for revascularization procedures have worse outcomes.
Methods:
We identified a retrospective cohort of 300 CLI patients who underwent revascularization between January 1, 2000 and December 31, 2010 at a single academic medical center. Patients were stratified into 2 groups based on distance greater than or less than 100 miles from the referral center. The association between travel distance and outcome measures including length of stay (LOS), postoperative functional status, hospital disposition, patient follow-up, and amputation-free survival (AFS) were evaluated using Cox proportional hazard models controlling for patient comorbidities and type of revascularization procedure.
Results:
One hundred eighteen (39%) patients travelled >100 miles for CLI revascularization. The 2 groups had similar baseline characteristics. Overall, 211 (70%) patients underwent an open revascularization, 60 (20%) an endovascular, and 29 (10%) a hybrid procedure. Those living >100 miles away less commonly underwent an endovascular procedure (14% vs. 24%, P = 0.05). LOS was similar between near and far groups (7.3 vs. 8.9 days, P = 0.1), as was postoperative functional status (ambulatory 73% vs. 68%, P = 0.34) and discharge to home (68% vs. 74%, P = 0.34). Long-term follow-up (mean 2.07 years) was similar between distance groups (P = 0.6). Five-year AFS (73% vs. 56%, P = 0.02) was superior in the distance >100 group. In the multivariate analysis, distance >100 miles (hazard ratio [HR] 0.6, P = 0.05), preoperative warfarin use (HR 0.5, P = 0.02), and independent ambulatory status (HR 0.5, P = 0.002) were associated with improved AFS.
Conclusions:
Patient referral distance did not adversely affect AFS or long-term follow-up after revascularization for CLI. Patients traveling from rural settings for revascularization can expect similar outcomes as patients located near tertiary centers.
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