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Published on: September 4, 2012
Expression patterns of miR-146a and miR-146b in mastitis infected dairy cattle
Xing Ping Wang1, Zhuo Ma Luoreng1, Lin Sen Zan2
1College of Animal Science and Technology, National Beef Cattle Improvement Center, Northwest A&F University, Yangling, Shaanxi, China; Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China.
Abstract:
This study reports a significant up-regulation of bta-miR-146a and bta-miR-146b expression levels in bovine mammary tissues infected with subclinical, clinical and experimental mastitis. Potential target genes are involved in multiple immunological pathways. These results suggest a regulatory function of both miRNAs for the bovine inflammatory response in mammary tissue.

