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Updated: Mar 16, 2026

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
Published on: May 21, 2018
[Research Progress on Inflammasome and Cancer-associated Thrombosis-Review]
1Institute of Hematology, Clinical Medical College of Yangzhou University,Subei People's Hospital of Jiangsu Province,Yangzhou 225001,Jiangsu Province,China.
Abstract:
Inflammasome is a complex of protein, which can recognize pathogen molecules and pathogens simulating human heat shock protein via pattern recognition receptors, thus it causes their own activation, sensitizes NF-κB pathway, induces the production of inflammatory mediators, leads the chronic inflammation and promotes thrombosis. Some studies reported that nearly 17% of the new tumors can be caused by chronic inflammation, and it seems that there is a complicated relationship between inflammasome and cancer-associated thrombosis.This article summarizes the correlation between inflammasome and cancer-associated thrombosis, and some of these theories have confirmed the relationship between them.
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