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Updated: Mar 16, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
PARANEOPLASTIC VITELLIFORM MACULOPATHY IN THE SETTING OF CHOROIDAL MELANOMA: EVOLUTION OVER ONE YEAR
Aaron Nagiel1, Daniel B Rootman, Tara A McCannel
1*Retina Division, Stein Eye Institute, Los Angeles, California; †Orbital and Ophthalmic Plastic Surgery Division, Stein Eye Institute, Los Angeles, California; and ‡Doheny Eye Institute, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Background:
To illustrate the evolution of paraneoplastic vitelliform maculopathy over one year using optical coherence tomography.
Methods:
Observational case report.
Results:
A 65-year-old man with a history of ocular melanocytosis and choroidal melanoma of the left eye treated with plaque brachytherapy 3 years prior returned for his yearly follow-up visit. The visual acuity in the right eye was 20/20. Subtle thickening of the interdigitation zone layer was noted on optical coherence tomography. Over the following year, multifocal vitelliform detachments developed with progressive enlargement and coalescence of the lesions. Paraneoplastic vitelliform maculopathy developed in the fellow eye of a patient with local recurrence of previously treated choroidal melanoma.
Conclusion:
Paraneoplastic vitelliform maculopathy may develop in the fellow eye of a patient with local recurrence of their previously treated choroidal melanoma with no clinical evidence of systemic metastasis.
