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Updated: Mar 16, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[TUBERCULOSIS GRANULOMA: THE CURRENT VIEW OF ITS IMMUNOGENESIS AND CELLULAR COMPOSITION]
Abstract:
The review presents the available basic scientific data characterizing the current views of the immunological homeostasis of intact lung tissue, the population and subpopulation composition of the cells forming a tuberculosis granuloma, as well as their phenotypic characteristics, the factors contributing to macrophageal transformation into epitheliod cells and Pirogov-Langhans giant cells, and the effect of mycobacterial antigens on this process.
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