Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

453
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
453
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

2.2K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.2K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

618
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
618
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

9.9K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
9.9K
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

2.7K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.7K
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

1.5K
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Special issue: Quantitative and precise measurements in conventional (scanning) electron microscopy and electron tomography.

Micron (Oxford, England : 1993)·2026
Same author

A tragedy after successful endovascular intervention; a complication of suture-mediated closure and repair system.

Cardiovascular intervention and therapeutics·2026
Same author

Combined use of drug-eluting stent and drug-coated balloon for tandem lesion with spontaneously recanalized coronary thrombus: insights from optical coherence tomography.

European heart journal. Case reports·2026
Same author

Dual Intracardiac Thromboses Associated With Dilated Coronary Sinus and Persistent Left Superior Vena Cava.

JACC. Case reports·2026
Same author

Reproducibility and Validity of a Food Intake Survey Developed for Implementation via Digital Health for Patients With or at Risk for Cardiovascular Disease.

Circulation reports·2025
Same author

Once- or twice-daily thoracic radiation in limited-stage small-cell lung cancer treated with concurrent chemoradiotherapy.

The Cochrane database of systematic reviews·2025
Same journal

[Development of novel therapeutics for multiple myeloma and improvement of drug lag].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Clinical pharmacy services to patients of immunomodulatory drugs].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Therapeutic drug monitoring of the new anti-myeloma drugs in the treatment of multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Prognostic value of minimal residual disease assessment using next-generation sequencing in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[The evaluation of minimal residual disease in multiple myeloma by an allele-specific oligonucleotide real-time PCR].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Evaluation of minimal residual disease in myeloma by multiparametric flow cytometry].

Nihon rinsho. Japanese journal of clinical medicine·2019
See all related articles

Related Experiment Video

Updated: Mar 16, 2026

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.5K

[Thrombolytic agent]

Ken Harada

    Nihon Rinsho. Japanese Journal of Clinical Medicine
    |August 19, 2016
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
    07:50

    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

    Published on: June 4, 2021

    3.2K
    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
    06:12

    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots

    Published on: July 21, 2023

    1.1K

    Related Experiment Videos

    Last Updated: Mar 16, 2026

    Prehospital Thrombolysis: A Manual from Berlin
    05:52

    Prehospital Thrombolysis: A Manual from Berlin

    Published on: November 26, 2013

    22.5K
    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
    07:50

    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

    Published on: June 4, 2021

    3.2K
    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
    06:12

    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots

    Published on: July 21, 2023

    1.1K