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Published on: September 26, 2018
Cardiovascular risk assessment and treatment in chronic inflammatory disorders in primary care
G Emanuel1, J Charlton1, M Ashworth1
1Department of Primary Care and Public Health, King's College London, London, UK.
Insights
Cardiovascular risk assessment in rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) patients is suboptimal. Management of vascular risk factors requires improvement, especially regarding cardiovascular disease (CVD) risk score calculation in primary care.
Area of Science:
- Rheumatology
- Gastroenterology
- Cardiology
- Primary Care Medicine
Background:
- Rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) are associated with increased cardiovascular disease (CVD) risk.
- Effective management of CVD risk factors is crucial for these patient populations.
- Primary care plays a vital role in assessing and managing vascular risk.
Purpose of the Study:
- To compare the assessment and management of cardiovascular (CV) risk factors in patients with RA and IBD against matched controls.
- To evaluate trends in CV risk factor assessment and treatment over time relative to diagnosis.
- To identify gaps in vascular risk management within primary care for RA and IBD patients.
Main Methods:
- A matched cohort study utilizing primary care electronic health records.
- Identification of RA, IBD patients, and matched controls from London general practices.
- Comparison of CV risk factor assessment (blood pressure, BMI, cholesterol, smoking) and treatment in the years before, after, and 5 years post-diagnosis.
Main Results:
- Patients with RA and IBD showed higher rates of CV risk factor measurement compared to controls, though this difference diminished over 5 years.
- RA patients had higher antihypertensive prescription rates, while IBD patients had higher statin prescription rates pre-diagnosis.
- Incomplete CV risk assessment was prevalent, with QRISK scores calculable for only 17% of RA patients and 11% of IBD patients.
Conclusions:
- Vascular risk assessment and management in primary care for RA and IBD patients are suboptimal.
- There is a significant need for improved calculation and recording of CVD risk scores in these patient groups.
- Enhanced primary care strategies are required to optimize cardiovascular risk management for individuals with RA and IBD.
Objective:
To compare differences in cardiovascular (CV) risk factors assessment and management among patients with rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) with that of matched controls.
Methods:
A matched cohort study was conducted using primary care electronic health records for one London borough. All patients diagnosed with RA or IBD, and matched controls registered with local general practices on 12th of January 2014 were identified. The study compared assessment and treatment of CV risk factors (blood pressure, body mass index, cholesterol and smoking) in the year before, the year after, and 5 years after RA and IBD diagnosis.
Results:
A total of 1121 patients with RA and 1875 patients with IBD were identified and matched with 4282 and, respectively, 7803 controls. Patients with RA were 25% (incidence rate ratio, 1.25, 95% CI 1.12 to 1.35) more likely to have a CV risk factor measured compared with matched controls. The difference declined to 8% (1.08, 1.04 to 1.14) over 5 years of follow-up. The corresponding figures for IBD were 26% (1.26, 1.16 to 1.38) and 10% (1.10, 1.05 to 1.15). Patients with RA showed higher antihypertensive prescription rates during 5 years of follow-up (OR, 1.37, 95% CI 1.14 to 1.65) and patients with IBD showed higher statin prescription rates in the year preceding diagnosis (2.30, 1.20 to 4.42). Incomplete CV risk assessment meant that QRISK scores could be calculated for less than a fifth (17%) and clinical recording of CV disease (CVD) risk scores among patients with RA and IBD was 11% and 6%, respectively.
Conclusions:
The assessment and treatment of vascular risk in patients with RA and IBD in primary care is suboptimal, particularly with reference to CVD risk score calculation.
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