Related Experiment Video

Updated: Mar 16, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

4.6K

Incidence and Clinical Associations of Childhood Acute Pancreatitis

Abdalmonem A Majbar1, Eleri Cusick2, Paul Johnson3

  • 1National Institute for Health Research, Bristol Biomedical Research Unit in Nutrition and University of Bristol, United Kingdom; Bristol Royal Hospital for Children, Bristol, United Kingdom; a.a.majbar@bristol.ac.uk.

Pediatrics
|August 19, 2016
PubMed

Insights

Childhood acute pancreatitis (AP) is uncommon in the UK, with over one case diagnosed weekly. Pakistani children show a significantly higher incidence, warranting further research into this disparity.

Area of Science:

  • Pediatric Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Acute pancreatitis (AP) in children is a rare but serious condition.
  • Understanding the incidence and associations of childhood AP is crucial for effective management and prevention.

Purpose of the Study:

  • To determine the incidence of acute pancreatitis (AP) in children aged 0 to 14 years in the United Kingdom.
  • To identify the clinical associations and risk factors for childhood AP in the UK.

Main Methods:

  • A nationwide surveillance study was conducted using the British Pediatric Surveillance Unit from April 2013 to April 2014.
  • Data collection involved monthly reporting of new AP cases in children under 15, with a 1-year administrative follow-up.

Main Results:

  • The UK incidence of childhood AP was 0.78 per 100,000 children/year.
  • Pakistani children had a sevenfold higher incidence (4.55 per 100,000) compared to white children (0.63 per 100,000).
  • Idiopathic AP accounted for 37% of cases, followed by drug therapy (19%) and gallstones (13%).

Conclusions:

  • Childhood AP is diagnosed weekly in the UK, highlighting its continued relevance.
  • Significant shifts in AP associations have occurred since the 1970s-80s.
  • The overrepresentation of Pakistani children with AP requires further investigation.
Abstract

More Related Videos

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

1.3K
Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line06:24

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

970

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.0K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.4K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
842
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
456
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
3.2K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
990